[Post operative complications after neoadjuvant systemic therapy in primary breast cancer treatment - Case-control study].
Identifieur interne : 000889 ( Main/Exploration ); précédent : 000888; suivant : 000890[Post operative complications after neoadjuvant systemic therapy in primary breast cancer treatment - Case-control study].
Auteurs : D. Marszalek [Belgique] ; J C Noël [Belgique] ; P. Simon [Belgique]Source :
- Revue medicale de Bruxelles [ 0035-3639 ] ; 2016.
Abstract
The use of neoadjuvant systemic therapy (NST) for the primary breast cancer treatment has constantly increased. Initially used to improve breast-conserving surgery (BCS) rate as well as for patients with inflammatory or inoperable locally advanced breast cancer, today, NST is used as a test of chemosensitivity and predictive factor by assessing pathologic complete response. With the increasing use of NST, it is fundamental to establish if NST increases postoperative morbidity.. In our study, the postoperative complications associated with NST were examined. We analyzed the data obtained from patients undergoing treatment for breast cancer in a University Hospital between 2003-2014 in a case-control study. We selected 286 patients attributed to two groups according to the surgery type: Group A, 150 patients undergoing breast conserving surgery with axillary node dissection (75 cases after NST and 75 controls with surgery alone) and group B, 136 patients undergoing mastectomy with axillary node dissection (68 cases after NST and 68 controls). There was no statistically significant difference between both groups in post-operative recovery or the rates of complications: use of antibiotics, re-operation, hematoma, blood transfusion, healing problems, wound infection, lymphocele and lymphoedema. Our study supports the safety of NST and suggests that it is not associated with increased morbidity in the patients undergoing breast surgery as BSC or mastectomy with axillary node dissection.
PubMed: 28525174
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000A70
- to stream PubMed, to step Curation: 000A70
- to stream PubMed, to step Checkpoint: 000A70
- to stream Ncbi, to step Merge: 009098
- to stream Ncbi, to step Curation: 009098
- to stream Ncbi, to step Checkpoint: 009098
- to stream Main, to step Merge: 000890
- to stream Main, to step Curation: 000889
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Post operative complications after neoadjuvant systemic therapy in primary breast cancer treatment - Case-control study].</title>
<author><name sortKey="Marszalek, D" sort="Marszalek, D" uniqKey="Marszalek D" first="D" last="Marszalek">D. Marszalek</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Noel, J C" sort="Noel, J C" uniqKey="Noel J" first="J C" last="Noël">J C Noël</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Simon, P" sort="Simon, P" uniqKey="Simon P" first="P" last="Simon">P. Simon</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:28525174</idno>
<idno type="pmid">28525174</idno>
<idno type="wicri:Area/PubMed/Corpus">000A70</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A70</idno>
<idno type="wicri:Area/PubMed/Curation">000A70</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A70</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000A70</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A70</idno>
<idno type="wicri:Area/Ncbi/Merge">009098</idno>
<idno type="wicri:Area/Ncbi/Curation">009098</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">009098</idno>
<idno type="wicri:doubleKey">0035-3639:2016:Marszalek D:post:operative:complications</idno>
<idno type="wicri:Area/Main/Merge">000890</idno>
<idno type="wicri:Area/Main/Curation">000889</idno>
<idno type="wicri:Area/Main/Exploration">000889</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Post operative complications after neoadjuvant systemic therapy in primary breast cancer treatment - Case-control study].</title>
<author><name sortKey="Marszalek, D" sort="Marszalek, D" uniqKey="Marszalek D" first="D" last="Marszalek">D. Marszalek</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Noel, J C" sort="Noel, J C" uniqKey="Noel J" first="J C" last="Noël">J C Noël</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Simon, P" sort="Simon, P" uniqKey="Simon P" first="P" last="Simon">P. Simon</name>
<affiliation wicri:level="1"><nlm:affiliation>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Hôpital Erasme, Service de Gynécologie-Obstétrique, ULB, Route de Lennik 808, Anderlecht</wicri:regionArea>
<wicri:noRegion>Anderlecht</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Revue medicale de Bruxelles</title>
<idno type="ISSN">0035-3639</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The use of neoadjuvant systemic therapy (NST) for the primary breast cancer treatment has constantly increased. Initially used to improve breast-conserving surgery (BCS) rate as well as for patients with inflammatory or inoperable locally advanced breast cancer, today, NST is used as a test of chemosensitivity and predictive factor by assessing pathologic complete response. With the increasing use of NST, it is fundamental to establish if NST increases postoperative morbidity.. In our study, the postoperative complications associated with NST were examined. We analyzed the data obtained from patients undergoing treatment for breast cancer in a University Hospital between 2003-2014 in a case-control study. We selected 286 patients attributed to two groups according to the surgery type: Group A, 150 patients undergoing breast conserving surgery with axillary node dissection (75 cases after NST and 75 controls with surgery alone) and group B, 136 patients undergoing mastectomy with axillary node dissection (68 cases after NST and 68 controls). There was no statistically significant difference between both groups in post-operative recovery or the rates of complications: use of antibiotics, re-operation, hematoma, blood transfusion, healing problems, wound infection, lymphocele and lymphoedema. Our study supports the safety of NST and suggests that it is not associated with increased morbidity in the patients undergoing breast surgery as BSC or mastectomy with axillary node dissection.</div>
</front>
</TEI>
<affiliations><list><country><li>Belgique</li>
</country>
</list>
<tree><country name="Belgique"><noRegion><name sortKey="Marszalek, D" sort="Marszalek, D" uniqKey="Marszalek D" first="D" last="Marszalek">D. Marszalek</name>
</noRegion>
<name sortKey="Noel, J C" sort="Noel, J C" uniqKey="Noel J" first="J C" last="Noël">J C Noël</name>
<name sortKey="Simon, P" sort="Simon, P" uniqKey="Simon P" first="P" last="Simon">P. Simon</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000889 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000889 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:28525174 |texte= [Post operative complications after neoadjuvant systemic therapy in primary breast cancer treatment - Case-control study]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28525174" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |